Four major circuits in the brain release dopamine: (1) nigrostriatal pathway – associated with divergent thinking, involved in generating eye movement, bodily movement, and thinking about movement; (2) meso-cortical pathway responsible for convergent thinking, a more emotional pathway responsible; (3) mesolimbic area involved in desire and reward, associated with addictive behavior; (4) tuberoinfundibular pathway regulates prolactin secretion by the pituitary gland
- You cannot selectively amplify dopamine in just one pathway with drugs or stimulants – dopamine transmission will enhance across all 4 pathways
- L tyrosine and phenylethylamine can increase dopamine